Mathematical Modeling of Blood Clot Fragmentation During Flow-Mediated Thrombolysis
نویسندگان
چکیده
منابع مشابه
Mathematical modeling of blood clot fragmentation during flow-mediated thrombolysis.
A microscale mathematical model of blood clot dissolution based on coarse-grained molecular dynamics is presented. In the model, a blood clot is assumed to be an assembly of blood cells interconnected with elastic fibrin bonds, which are cleaved either biochemically (bond degradation) or mechanically (bond overstretching) during flow-mediated thrombolysis. The effect of a thrombolytic agent on ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2013
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2013.01.029